Best Enzyme Cleaners for Dog Urine

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Getting dog urine out of your carpeting can be a struggle. If you don’t pull up the entire stain, your house will start to smell as soon as it gets warm. An enzyme cleaner can break down the particles that cause odors, eliminating the small. When the reaction is finished, the resulting ammonia and carbon dioxide evaporate into the air. It’s like the stain was never there.

The Best Enzyme Cleaners for Dog Urine

ProductAmount in BottleOrganicTypes of Surfaces
#1. Rocco & Roxie
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32 ouncesNoAll fabric surfaces
#2. Sunny & Honey

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32 ouncesYesAll fabric surfaces, hardwood, leather
#3. Bubbas

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128 ouncesYesAll fabric surfaces, hardwood, clothing
#4. Petzyme

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32 ouncesYesAll fabric surfaces, all water-safe surfaces
#5. Simple Solution

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32 ouncesNoAll fabric surfaces, clothing, all water-safe surfaces

#1. Rocco & Roxie Professional Strength Stain and Odor Eliminator

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This enzyme cleaner is consistently rated as one of the best on the market. While it’s not the cheapest option available, it’s still very affordable. In addition to eliminating odors and dog urine stains, the cleaner also gets rid of urine residue.

The enzymes begin feeding on bacteria, ammonia, and other organic matter upon contact. If you soak a tough stain, the stain should be completely or almost completely gone in the next 24 hours.

The cleaner has been certified safe to use around children and pets. It doesn’t have chlorine or other hazardous chemicals. No residue is left when it finishes cleaning, and the surface is dry and clear upon completion.

The Carpet and Rug Institute has given this cleaner a seal of approval because of its safe and effective formula. No chemicals are released into the air, helping minimize skin reactions and letting you breathe easier.

#2. Sunny & Honey Pet Stain & Odor Miracle

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This enzyme cleaner is similarly priced to the Rocco & Roxie one, and there’s the same amount of liquid in the bottle. In addition to removing dog urine, the cleaner can neutralize dog feces, drool, and vomit. Once the bacteria go away, so do the stains.

The Rocco & Roxie cleaner is optimized for use on fabric surfaces. This one, on the other hand, can handle fabric surfaces, leather, hardwood, tile, and car upholstery. The formula is safe enough to clean pet beds and your child’s bedding. It can also be used on your furniture.

Since the cleaner uses natural enzymes rather than harsh chemicals, the cleaner is safe for use around children and pets. In addition, the cleaner is manufactured in the United States, and ten percent of the profits go directly to animal shelters and animal rescues.

#3. Bubbas Super Strength Commercial Enzyme Cleaner

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This is the cleaner you want if you’re a professional who works in a lot of homes with pets. It’s also good if you work in a veterinarian office or animal shelter. Unlike the other bottles on this list, this massive jug holds 128 total ounces.

There are billions of enzymes that become activated immediately upon contact with dog urine and other stains. Since the enzymes don’t activate until they touch a mess, the strength of the solution doesn’t degrade over time. Other solutions use active enzymes that die off and lose potency.

The cleaner is formulated for use in all the surfaces in your house, laundry room, and car. You can clean pee out of your upholstery, remove urine from your clothes before washing them, and effectively spot treat your carpet and hard flooring.

#4. Petzyme Pet Stain Remover and Odor Eliminator

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This enzyme-based cleaner can permanently destroy dog urine stains and odors. Unlike many other cleaners, this one is formulated to remove cat urine as well, so it’s a good choice if you have both dogs and cats.

All you have to do is spray the cleaner at the spot needing treatment. It’s safe for use on fabrics, upholstery, carpeting, and any other water-safe surface. Since the odor-causing bacteria are neutralized, the odors disappear for good.

The formula is non-toxic and environmentally friendly. It’s safe to use for dogs, cats, birds, and small caged animals. You can even use it on concrete that dog urine has soaked into. If you have clothing, bedding, or sleeping bags soaked with pee, this cleaner is safe to use with them too.

If you have a laminated kitchen floor, you might want to choose this cleaner since it doesn’t damage the seal.

#5. Simple Solution Extreme Pet Stain and Odor Remover

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This is the most inexpensive enzyme cleaner on the list. Since each bottle has 32 ounces of solution, it’s a good choice if you’re on a strict budget. If you’re dealing with a lot of soaked-in dog urine, though, the cleaning power might not be powerful enough.

In comparison to the regular Simple Solution formula, this one has three times the cleaning strength to lift tougher urine stains. Like other enzyme cleaners, this cleaner uses bacteria and enzymes to break down and fully eliminate messes and smells.

This particular formula has been specifically made to target dog and cat messes. It’s safe to use around pets. In addition to carpeting and furniture, you can use the cleaner to remove messes from bedding, clothing, and fabric dog toys. The cleaner won’t perform very well on hard surfaces, though.

Final Thoughts

Any enzyme cleaner will do the trick as long as you let it work correctly. You should leave the carpet soaked with cleaner for 24 hours to get the full stain out.

The Rocco & Roxie stain cleaner is specifically formulated for dog and cat urine. It contains the enzymes that efficiently and effectively break down stains, and you don’t even need to wipe up afterward.

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