Best Hypoallergenic Sheets

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When you suffer from allergies, even something as simple as trying to sleep can become difficult. Bedding tends to trap allergens like dust and pet dander. This can lead to your skin becoming irritated, your nose getting stuffy, and your breathing being shallow. When the respiratory issues cause sleep apnea, your sleep can be disturbed entirely, leading to exhaustion and irritability.

There are hypoallergenic sheets that are both comfortable and easy to maintain. Not only are hypoallergenic sheets made from allergen-free material, but they also repel allergens. Most hypoallergenic sheets are very easy to clean with a lint roller or other simple tool, and you can wash them in your washer as well.

The material used in a sheet set makes a big difference. Most hypoallergenic sheets on the market use microfiber, which is made with synthetic material that’s silky and soft against your skin. However, if you don’t like the texture of microfiber, there are also options like bamboo fiber blends.

The Best Hypoallergenic Sheets

FeatureSizes AvailableMaterialPieces in Set
#1. Mellanni
Our Best Pick

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7Polyester microfiber4
#2. Tastelife

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3Microfiber4
#3. Cosy House Collection

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7Bamboo4

#1. Mellanni Brushed Microfiber Bedding Sheet Set

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The Mellanni bed sheet set is one of the most popular sets of sheets on the market, having been used by tens of thousands of people all over the world. It’s consistently ranked at the top of sheet sets for people with allergies. The four-piece set uses polyester microfiber fabric that’s stain, fade, and wrinkle-resistant.

One of the biggest selling points of this set is the versatility. There are seven total sizes to choose from: twin, XL twin, full, queen, king, California king, or split king. Even if you have an unusually-sized mattress, you should be able to get a sheet set that will suit it.

There are also a whopping forty-two different colors and styles available. Some are solid colors that range from neutral tones to pastels to deeply-saturated and bright colors. Some are more intricate patterns that use curves, zigzags, swirls, stripes, or lacy appearances. You can find a style and color that will suit any aesthetic, so you don’t have to settle for white.

The texture of the 1800 microfiber fabric is silky and soft. With this four-piece set, you get a fitted sheet, a flat sheet, and two pillowcases. The fitted sheet is a deep pocket design that has elastic around the entire bottom, making it easier to pull and tighten around the corners of the mattress.

Caring for this set is easy. It’s resistant to wrinkles, shrinkage, staining, and fading. The microfiber material is more durable than cotton, so you don’t have to worry about it wearing down or tearing over time. You can machine wash the set in cold water, and it will tumble dry quickly in the dryer.

Another one of the selling points of this set is that it comes with a lifetime guarantee from Mellanni. Most sheets aren’t built to last a lifetime, but these are an exception. If, at any point, you have problems with the sheets or decide they aren’t for you, you can receive your money back without needing to return the sheet set.


#2. Tastelife Deep Pocket Microfiber 1800 Bedding Sheets

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This set of sheets from Tastelife has a lot of similarities to the sheets offered by Mellanni. Like the Mellanni sheets, these sheets use hypoallergenic microfiber of the softest variety. They have a silky and smooth texture that’s easy to sleep on. The four-piece set includes two pillowcases, a fitted sheet, and a normal sleeping sheet.

The set doesn’t have as much variety of the Mellanni sheets, but it still comes with a good amount of versatility. You can get sheets that are sized for a twin bed, queen, or California king. Unfortunately, if you have an unusual mattress sizing or a standard king, you probably won’t be able to make the set comfortably fit it.

There are seven colors. They tend to be more pale and desaturated than the vibrant patterns available in the Mellanni sheets, so if you prefer a look that’s closer to pastel, these are the sheets for you. In addition to the standard white, they come in green, gold, royal blue, dark grey, sky blue, and navy blue.

The fitted sheet has elastic around the entire bottom of the sheet rather than just the corners, so it’s easy to fit deeply over your mattress. Caring for the set is easy. You don’t have to worry about fading, staining, or wrinkling. To wash the sheets, just throw them in the machine on cold. They’re more durable than cotton and can tumble dry in your dryer.

These sheets also come with a one hundred percent money back guarantee. The warranty lasts for one year from the date of purchase. Should you be unsatisfied with them for any reason within that time period, you can return the product to get your money back.


#3. Cosy House Collection Bamboo Sheet Set

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This luxurious set of sheets is different from either of the previous two options. Rather than using microfiber, these sheets are crafted with a blend of natural bamboo fibers. They resist wrinkles and fading. Available in seven sizes and thirteen colors, there’s a set that can suit anyone’s personal aesthetic. All the designs use solid colors rather than patterns, and the colors range from pale and neutral tones to highly-saturated purples and blues and greens.

If you have trouble with the texture of completely microfiber sheets, the bamboo blend may offer a nice difference. Rather than using one hundred percent microfiber or bamboo, these sheets blend forty percent microfiber with a sixty percent bamboo construction. This gives the sheets the texture of bamboo with the softness and durability of microfiber.

Since the sheets are available in so many sizes, they should be able to fit your mattress regardless of whether the size is standard or not. The four-piece set includes two pillowcases, a flat sheet, and a fitted sheet. The fitted sheet can create pockets of up to sixteen inches, allowing it to be pulled snugly and securely over the mattress.

The sheets use regenerated cellulose fiber from the rayon. This helps immensely with heat regulation during the night, making the sheet set both breathable and naturally hypoallergenic. When it’s hot, your body heat can dissipate so you don’t wake up sweating. At the same time, the sheets wrap and protect you snugly when it’s cold outside.

Caring for the sheets is easy. To avoid piling, you should wash them on cold and use low heat to tumble them dry. The construction uses tightly-knit threads and strong elastic to keep the sheets securely on the bed without tearing or loose threads.

All customer concerns are answered within 24 hours of query. In addition, you get a 100 percent money back guarantee and a lifetime warranty if you’re not satisfied. Should you have any issues with the sheets, just return the set to receive a refund.


Final Thoughts

The Mellanni sheets are some of the most versatile on the market. Available in seven sizes and forty-two colors, you’re able to find a type of sheet that matches any personal aesthetic. The sheets are made from polyester microfiber that’s some of the softest, most comfortable material available. Caring for the sheets is easy, and you also get a lifetime guarantee from the manufacturer. If you have any problem with the sheets, you can get your money back without even needing to return the set.

The Tastelife sheets are another ideal option made from high-quality, soft microfiber. Each piece in the set is stain-resistant and fade-resistant. You don’t have to worry about ironing the sheets, because they don’t wrinkle.

Unfortunately, these sheets are available in only three sizes, so if you have an unusual size or standard king bed, you might not be able to get a set that suits your mattress. There’s also a smaller color selection than with the Mellanni, with only seven colors available. That said, if you find the color and size that suits your aesthetic, these sheets are just as easy to care for as the Mellanni ones.

The Cosy House Collection sheets are a different type of offering. Rather than using microfiber and synthetic materials, these hypoallergenic sheets are crafted from a blend of natural bamboo. As such, they’re a little pricier than the other options. But if you don’t like the feel of microfiber and want a wrinkle-resistant, hypoallergenic sheet set with a different texture, this is the way to go. Thirteen colors are available in a variety of tones and brightness levels. You can order the sheets in seven different sizes, so you should have an option that suits your bed.

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